The simplest way to wash your mouthguard is to brush it every day, just as you do your teeth. You may also wash it with mouthwash or with hydrogen peroxide, a mild bleach solution, soapy water, or denture cleaners. You never want to soak your mouthguard in these solutions for an extended period. Soaking in anything other than water may damage the plastics used to create your mouthguard. Finish your cleaning by rinsing with plain water.
Failing to properly wash your mouthguard after each use can result in introducing unhealthy bacteria into your mouth, speeding up gum recession and tooth decay. The Auburn office of Rock Creek Dental encourages you to brush your teeth at least twice every day and your mouthguard after every use.
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